Bruzzone received his Degree in Architecture from the University of Buenos Aires (1995). He carried out art studies in the Scholarship Program coordinated by Guillermo Kuitca (1994-1995 and 1997-1998), and with Juan Doffo (1990-1994). He was awarded a refresher grant at the Cité Internationale des Arts, Paris (1996-1997). He has also carried out studies in photography, scenography and color, and electronic engineering.

Bruzzone’s series are the result of a complex system involving research in visual archives to build and manipulate scale models that are subsequently photographed. His work questions the role of photography as an objective, neutral register, while exploring processes of artificiality and simulation in photographic representation, along similar lines to those examined by James Casebere or Thomas Demand. Bruzzone focuses obsessively on the creation of faithful and exact transcriptions of reality, but insofar they enable him to capture highly emotional moments lost in time.

His most recent individual exhibitions include: Stars at the Nara Roesler Gallery, Sao Paulo, Brazil (2004); Arquitectura Escéptica (Skeptical Architecture) , curated by Lucas Fragasso, Dabbah Torrejón Gallery, Buenos Aires, Argentina (2005); Parque de Atracciones (Fairground) , Luis Fernando Pradilla Gallery, Madrid, Spain (2002), and Parque de Diversiones (Amusement Park) , curated by Laura Buccellato, Modern Art Museum of Buenos Aires, Argentina. Since the outset of the 90s he has taken part in numerous international exhibitions and curatorships in various art centers in Latin America, Europe and North America.

He has participated in the Santiago de Chile Biennial, Chile (2002); the Sao Paulo Biennial, Brazil (1999); the Venice International Biennial, Italy (1999), and the Mercosur Biennial, Porto Alegre, Brazil (1999). His work forms part of the Latin American Art Museum of Buenos Aires, Argentina; the Contemporary Art Museum of Rosario, Argentina; the Contemporary Art Museum of Santiago de Chile, Chile; the Modern Art Museum of the City of Buenos Aires, Argentina, and the National Fine Arts Museum, Argentina.

The 2006 interview by Maria Fernanda Cartagena is a general review of the motivations behind his work, and focuses on two of his latest series, created in 2006 --one on the legendary, extravagant rock group Kiss, and another on Shaila, a Buenos Aires brothel that no longer exists.